Nurse job market in Saint Louis, MO (2026)
The Nurse job market in Saint Louis, MO is moderately active, with 284 open positions across 15+ employers. Hiring momentum is strong, with 56 new listings in the past month and 32 in the last week alone.
What can you expect to earn?
The median salary for Nurse roles in Saint Louis, MO is $68,700, with most positions paying between $60,000 and $100,000. Top performers can earn $115,000 or more at the 90th percentile. Note that 96% of listings in this market don't disclose salary, so actual compensation varies — especially for negotiable roles. For higher compensation, consider Chicago, IL where the median is $125,000.
Skills that employers want
Analysis of job descriptions in Saint Louis, MO shows the most requested skills are Nursing, Patient Care, Customer Service, BLS, EHR, and CPR. Including these keywords in your resume can significantly improve your ATS match rate. Our Nurse resume example shows how to integrate these naturally.
Who's hiring?
The most active employers for Nurse positions in Saint Louis, MO include Bestica, Mercy, Archdiocese of St. Louis, ScionHealth, and Cooperative Home Care, Inc. Use JobsChat AI to filter by specific companies or discover employers that match your preferences.
Remote & flexible work
1% of Nurse jobs in Saint Louis, MO offer remote or hybrid work (3 positions). This role is predominantly on-site, though some employers are beginning to offer hybrid options.
Ready to apply?
Start with our Nurse resume example. Pair it with a tailored cover letter. Then use JobsChat AI to search all 284 positions and generate application materials in minutes. Browse Nurse jobs in other cities or explore all jobs in Saint Louis, MO.